The chemical name of xylazine hydrochloride is 2,6-xylidinethiazine, which belongs to the -adrenergic receptor agonist. It has particular sedative, analgesic and muscle relaxation effects on various animals. It is often used alone or in combination with other drugs. Anaesthesia for dogs, cats, pigs and other animals. It is rapidly absorbed by intramuscular injection, with the onset of action within 15 to 20 minutes and 5 to 10 minutes after intravenous injection.
The adequate time of one injection is about 1 to 2 hours. It has high fat solubility and can enter most tissues, with the highest concentration in the central nervous system and renal tissue. The amount passing through the placenta is limited, and fetal inhibition is less likely.
Surgeons favour xylazine because of its good anaesthetic effect. When xylazine hydrochloride is widely used in clinical anaesthesia, many studies have conducted in-depth discussions on its anaesthesia effect. However, its impact of it on the function of vital organs in animals has not been paid enough attention to after entering the body.
This experiment intends to study the changes in serum and related indexes of liver and kidney function after anaesthesia with xylazine hydrochloride in dogs, and evaluate its influence on liver and kidney function, to provide a reference for clinical medication and improve the safety of the anaesthetic medication. With the rapid development of today's society, the pet dog-related industries are developing increasingly vigorously, and more and more pet dogs are being raised. There is also an increasing number of pet dog diseases caused by various causes.
In various everyday pet operations such as sterilization, cesarean section and orthopaedic surgery, the quality of anaesthetics directly affects the process and quality of the procedure. Therefore, anaesthesia with ideal, minor side effects and a wide range of safety is selected. Medicine is crucial. However, many anaesthetics have disadvantages: poor anaesthesia effect, short action time, substantial toxicity, small safety range, and high price. References in Animal Husbandry and Veterinary Medicine"